BDBM576237 WO2022109573, Compound 36
SMILES Nc1cc(c2nc1-c1nnc(o1)C(=O)CCCCC[C@@H]1CCCN21)C(F)(F)F
InChI Key InChIKey=HJVIDBIMHUNDKL-SNVBAGLBSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 576237
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Vertex Pharmaceuticals
WIPO
Vertex Pharmaceuticals
WIPO
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair