BDBM577196 US11472811, Example 1B

SMILES Nc1nc2n(ncc2c2nc(nn12)-c1ccco1)[C@@H](C(=O)NCc1ccccc1)c1ccccc1

InChI Key InChIKey=HHAPSKPCJCLLPK-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577196   

TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577196(US11472811, Example 1B)
Affinity DataIC50:  0.700nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent