BDBM577342 (R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-N-((6-methoxypyridin-2-yl)methyl)-2-phenylpropanamide::US11472811, Example 112B

SMILES COc1cccc(CNC(=O)[C@@](C)(c2ccccc2)n2ncc3c2nc(N)n2nc(nc32)-c2ccco2)n1

InChI Key InChIKey=DLSCQTQFORIIOM-AREMUKBSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577342   

TargetAdenosine deaminase(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM577342((R)-2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1...)
Affinity DataIC50:  1.20nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent