BDBM578438 (R)—N-(4-(1H-pyrazol-4-yl)phenyl)-2-(3-methoxyphenyl)-2-((2-(methylamino)ethyl)amino)acetamide::US11479533, Example 62

SMILES CNCCN[C@@H](C(=O)Nc1ccc(cc1)-c1cn[nH]c1)c1cccc(OC)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 578438   

TargetRho-associated protein kinase 1 [1-535](Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM578438((R)—N-(4-(1H-pyrazol-4-yl)phenyl)-2-(3-methoxyphen...)
Affinity DataIC50:  3nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2 [1-552](Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM578438((R)—N-(4-(1H-pyrazol-4-yl)phenyl)-2-(3-methoxyphen...)
Affinity DataIC50:  1.80nMAssay Description:Compounds activities were measured by Z'-lyte kinase kit (ThermoFisher Scientific). The percent inhibition rate was calculated by normalizing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent