BDBM578738 US11479543, Compound I-50

SMILES CN1c2cc(ccc2OC[C@H](NC(=O)n2cc(Cc3ccc(F)nc3F)cn2)C1=O)C#CC(C)(C)O

InChI Key InChIKey=SNNGFLVCFNOZKV-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578738   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM578738(US11479543, Compound I-50)
Affinity DataIC50:  181nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent