BDBM580179 6-[4-Ethylsulfonyl-2-(trifluoromethyl)piperazin-1-yl]-4-(2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyridin-2-one::US11498919, Example 73

SMILES CCS(=O)(=O)N1CCN(C(C1)C(F)(F)F)c1cc(cc(=O)[nH]1)-c1ccnc2[nH]c(C)cc12

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580179   

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Sprint Bioscience

US Patent
LigandPNGBDBM580179(6-[4-Ethylsulfonyl-2-(trifluoromethyl)piperazin-1-...)
Affinity DataIC50: <5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent