BDBM581246 5-(3-(2-(thiazol-2- yl)ethynyl)phenoxy)-1H-1,2,3- triazole-4-carboxylic acid::US11504367, Example 342

SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1nccs1

InChI Key InChIKey=LOJOMBNKBKVIPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581246   

Target2-Hydroxyacid oxidase 1(Homo sapiens (Human))
Oxalurx

US Patent
LigandPNGBDBM581246(5-(3-(2-(thiazol-2- yl)ethynyl)phenoxy)-1H-1,2,3-...)
Affinity DataIC50:  2nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent