BDBM581287 (2S)-2-[(3-chloro-5-{[(2,4-diamino- 6-oxo-1,6-dihydropyrimidin-5 yl)carbamoyl]amino}pyridin-2- yl)formamido]pentanedioic acid::US11504368, Example 5

SMILES Nc1nc(N)c(NC(=O)Nc2cnc(C(=O)N[C@@H](CCC(O)=O)C(O)=O)c(Cl)c2)c(=O)[nH]1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581287   

TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Homo sapiens (Human))
Thomas Helledays Stiftelse FÖR Medicinsk Forskning

US Patent
LigandPNGBDBM581287((2S)-2-[(3-chloro-5-{[(2,4-diamino- 6-oxo-1,6-dihy...)
Affinity DataIC50:  15nMAssay Description:To determine the IC50 value of a compound, an 11-concentration dose-response curve with 3-fold difference in concentration between assay points was g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent