BDBM581757 US11512087, Example 1

SMILES CC(C)n1nc(-c2ccc3[nH]ccc3c2)c2c(N)nc(Nc3cn(C)nc3C)nc12

InChI Key InChIKey=HXKNWNXWDIVAGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581757   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM581757(US11512087, Example 1)
Affinity DataIC50: >1.00E+4nMAssay Description:Tyrosine phosphorylation of Lck was performed by using Z′-LYTE Kinase Assay Kit-Tyr 2 Peptide (Invitrogen) containing the following reagents (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM581757(US11512087, Example 1)
Affinity DataIC50:  2.10nMAssay Description:Measurement of an inhibitory activity on Brk enzyme was performed by using LanthaScreen (registered trademark) system (Invitrogen) in accordance with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent