BDBM581831 US11512087, Example 13-1

SMILES CC(C)n1cc(-c2ccc(C#N)c3[nH]ncc23)c2c(N)nc(Nc3ccc(cc3F)S(C)(=O)=O)nc12

InChI Key InChIKey=FCJNCMVGJIGMEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581831   

TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM581831(US11512087, Example 13-1)
Affinity DataIC50: >1.00E+4nMAssay Description:Tyrosine phosphorylation of Lck was performed by using Z′-LYTE Kinase Assay Kit-Tyr 2 Peptide (Invitrogen) containing the following reagents (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM581831(US11512087, Example 13-1)
Affinity DataIC50:  3.30nMAssay Description:Measurement of an inhibitory activity on Brk enzyme was performed by using LanthaScreen (registered trademark) system (Invitrogen) in accordance with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent