BDBM582019 US11518754, Compound (R)-4

SMILES Cc1cnccc1CN1C[C@H](CC1=O)c1ccc(F)c(F)c1

InChI Key InChIKey=JYDWVNMFKWAUNZ-AWEZNQCLSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 582019   

TargetSynaptic vesicle glycoprotein 2A(Rattus norvegicus)
Yale University

US Patent
LigandPNGBDBM582019(US11518754, Compound (R)-4)
Affinity DataKi:  2.08nMAssay Description:For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSynaptic vesicle glycoprotein 2A(Rattus norvegicus)
Yale University

US Patent
LigandPNGBDBM582019(US11518754, Compound (R)-4)
Affinity DataIC50:  12.6nMAssay Description:For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent