BDBM585731 8-cyclopropyl-1-(2,6- dichlorophenyl)-5-(2,3- dihydroxypropoxy)-2-methyl-1,6- naphthyridin-4(1H)-one::US11530213, Example 52

SMILES Cc1cc(=O)c2c(OCC(O)CO)ncc(C3CC3)c2n1-c1c(Cl)cccc1Cl

InChI Key InChIKey=PGJVAYQMCYJFFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585731   

TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585731(8-cyclopropyl-1-(2,6- dichlorophenyl)-5-(2,3- dihy...)
Affinity DataIC50:  73nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent