BDBM585734 3-chloro-2-(8-chloro-2- cyclopropyl-5-(2,3- dihydroxypropoxy)-4-oxo-1,6- naphthyridin-1(4H)-yl)benzonitrile::US11530213, Example 55

SMILES OCC(O)COc1ncc(Cl)c2n(c(cc(=O)c12)C1CC1)-c1c(Cl)cccc1C#N

InChI Key InChIKey=DCKMLYPIFNABIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585734   

TargetG protein-activated inward rectifier potassium channel 1/4(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM585734(3-chloro-2-(8-chloro-2- cyclopropyl-5-(2,3- dihydr...)
Affinity DataIC50:  54nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent