BDBM586474 US11530244, Compound 472

SMILES CC(C)C[C@@H]1[N@@]2CC[C@H](NC(=O)[C@H](Cc3c[nH]c4ccc(F)cc34)NC(=O)[C@H](Cc3c[nH]c4ccc(F)cc34)NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CCSCc3cccc(CSC[C@H](NC(=O)[C@]4(C)CCCN4C(=O)[C@H](Cc4ccc(O)cc4)NC1=O)C(N)=O)c3)C2=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 586474   

TargetProprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM586474(US11530244, Compound 472)
Affinity DataIC50:  50nMAssay Description:The PCSK9 Alexa FRET Standard assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent A (KD=83 nM). A s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent