BDBM589848 US11559538, Example 102::US11559538, Example 103

SMILES CCCOc1cc(ccc1OC)-c1nc(COC)cc(n1)C1COB(O)C1

InChI Key InChIKey=CAAZYLXQTJICMS-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589848   

TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  5.85nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  1.24E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  2.07nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  0.760nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  1.43nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  487nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  0.830nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589848(US11559538, Example 102 | US11559538, Example 103)
Affinity DataIC50:  3.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent