BDBM589850 US11559538, Example 104::US11559538, Example 105::US11559538, Example 106

SMILES CCCOc1cc(ccc1OCC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=CIJQFZFAGHEWAO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589850   

TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  3.58nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  750nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  29.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  5.46nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  3.20nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  3.42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  14.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterferon gamma receptor 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  5.46nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  1.83nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  2.09E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  16.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589850(US11559538, Example 104 | US11559538, Example 105 ...)
Affinity DataIC50:  490nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent