BDBM589895 US11559538, Example 147::US11559538, Example 148
SMILES CCCOc1cc(ccc1OC)-c1nc(ns1)C1COB(O)C1
InChI Key InChIKey=LBADOWKZXSXFPE-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 589895
Affinity DataIC50: 0.240nMAssay Description:Inhibition of human PDE4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 0.440nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer
US Patent
Pfizer
US Patent
Affinity DataIC50: 0.240nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair