BDBM589990 (R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1-(3-fluorobicyclo[1.1.1]pentan-1-yl)-1H-imidazol-2-yl)-2,2,2-trifluoroethanol::US11560366, Example 2a

SMILES Nc1ncc(cc1C(F)(F)F)-c1cn(c(n1)[C@@H](O)C(F)(F)F)C12CC(F)(C1)C2

InChI Key InChIKey=SHFUDMHWRPRGER-GWMXKSKGSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 589990   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM589990((R)-1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)...)
Affinity DataKd:  4.40nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent