BDBM590200 US11560385, Compound 10A::US11560385, Compound 15A

SMILES Cc1c(C(=O)CN2C3CCC2[C@@H](O)C3)c2ccc(CCC#N)cc2n1-c1ccc(Cl)cc1

InChI Key InChIKey=XBIMVGSHAOVKNH-JVPYDEADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 590200   

TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590200(US11560385, Compound 10A | US11560385, Compound 15...)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 14(Homo sapiens (Human))
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590200(US11560385, Compound 10A | US11560385, Compound 15...)
Affinity DataIC50: <50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent