BDBM59162 8047577

SMILES FC(F)(F)c1cccc(c1)N1C(=S)S\C(=C/c2ccc(o2)-c2ccc(Cl)cc2Cl)C1=O

InChI Key InChIKey=RPGCOTYVDOZKMV-ZDLGFXPLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59162   

TargetCoagulation factor VIII(Homo sapiens (Human))
University of Washington

LigandPNGBDBM59162(8047577)
Affinity DataIC50:  2.44E+3nMT: 2°CAssay Description:Inhibition of factor VIII C2 domain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VIII(Homo sapiens (Human))
University of Washington

LigandPNGBDBM59162(8047577)
Affinity DataIC50:  2.10E+3nMpH: 7.9Assay Description:Inhibition of factor X activation assay. A commercially available chromogenic assay that measures the rate of factor X activation to measure inhibit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VIII(Homo sapiens (Human))
University of Washington

LigandPNGBDBM59162(8047577)
Affinity DataIC50:  2.56E+3nMpH: 8.0Assay Description:Inhibition of factor VIII ELISA. The interaction between factor VIII and PS was measured by using an enzyme-linked immunoadsorbent assay (ELISA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed