BDBM592262 6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-(((1r,4R)-4- (5-cyclopropyl-1,3,4-oxadiazol-2- yl)cyclohexyl)amino)-N-((R)-2- fluoro-3-hydroxy-3- methylbutyl)nicotinamide::US11572362, Compound 41

SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1N[C@H]1CC[C@@H](CC1)c1nnc(o1)C1CC1)-c1ccc2cc(cnn12)C#N

InChI Key InChIKey=QVAXYGWTEGAFAZ-XMERXJNXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592262   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM592262(6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-(((1r,...)
Affinity DataIC50: <1nMAssay Description:The enzyme and peptide solution were incubated with compound for 15 minutes at room temp before the reaction was initiated by the addition of ATP. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent