BDBM592507 US11572371, Compound 19

SMILES CC(C)c1nnc(CC2N=C(c3c(C)c(C)sc3-n3c(C)nnc23)c2ccc(Cl)cc2)o1

InChI Key InChIKey=NHQWTZLQTWSZGU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 592507   

TargetBromodomain-containing protein 2(Homo sapiens (Human))
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM592507(US11572371, Compound 19)
Affinity DataIC50:  8.30nMAssay Description:Homogeneous time=resolved fluorescence (HTRF) was used to detect the binding of the compound to BRD4(D1 + D2) and BRDT (D1) proteins, and the AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM592507(US11572371, Compound 19)
Affinity DataIC50:  51nMAssay Description:Homogeneous time=resolved fluorescence (HTRF) was used to detect the binding of the compound to BRD4(D1 + D2) and BRDT (D1) proteins, and the AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM592507(US11572371, Compound 19)
Affinity DataIC50:  17nMAssay Description:Homogeneous time=resolved fluorescence (HTRF) was used to detect the binding of the compound to BRD4(D1 + D2) and BRDT (D1) proteins, and the AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Hinova Pharmaceuticals

US Patent
LigandPNGBDBM592507(US11572371, Compound 19)
Affinity DataIC50:  21nMAssay Description:Homogeneous time=resolved fluorescence (HTRF) was used to detect the binding of the compound to BRD4(D1 + D2) and BRDT (D1) proteins, and the AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent