BDBM598614 N-(4-(1H-pyrazol-4-yl)phenyl)-2-(3-(3-methoxyphenyl)pyrrolidin-1-yl)pyrimidin-4-amine::US11613531, Example 269

SMILES COc1cccc(c1)C1CCN(C1)c1nccc(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=BHWFJEBAUNSARM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598614   

TargetRho-associated protein kinase 2 [1-552](Human)
Kadmon

US Patent
LigandPNGBDBM598614(N-(4-(1H-pyrazol-4-yl)phenyl)-2-(3-(3-methoxypheny...)
Affinity DataIC50: 1.65E+3nMAssay Description:Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2023
Entry Details
US Patent