BDBM601172 US11634395, Example 200A::US11634395, Example 200B::US11634395, Example 207A::US11634395, Example 207B

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCCC2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 601172   

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601172(US11634395, Example 200A | US11634395, Example 200...)
Affinity DataIC50:  30nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601172(US11634395, Example 200A | US11634395, Example 200...)
Affinity DataIC50:  90nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601172(US11634395, Example 200A | US11634395, Example 200...)
Affinity DataIC50:  130nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601172(US11634395, Example 200A | US11634395, Example 200...)
Affinity DataIC50:  80nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent