BDBM601209 N-((1S,2R)-2-(3-chloro-6-fluoro-2-methylphenyl)-1-(5-oxo-4,5-dihydro-::US11634395, Example 229A::US11634395, Example 229B

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(F)c2c1OCCC2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Cl)c1C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 601209   

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601209(N-((1S,2R)-2-(3-chloro-6-fluoro-2-methylphenyl)-1-...)
Affinity DataIC50:  110nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601209(N-((1S,2R)-2-(3-chloro-6-fluoro-2-methylphenyl)-1-...)
Affinity DataIC50:  60nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent