BDBM602682 2-Chloro-5-[1-(2-isoindolin-2-yl- 6-methyl-4-oxo-chromen-8- yl)ethylamino]thiazole-4- carboxylic acid 2,2,2- trifluoroacetic acid::US11649227, Example 245::US20230286960, Example 245
SMILES CC(Nc1sc(Cl)nc1C(O)=O)c1cc(C)cc2c1oc(cc2=O)N1Cc2ccccc2C1
InChI Key InChIKey=VYKOUGSLTYMVTC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 602682
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Petra Pharma
US Patent
Petra Pharma
US Patent
Affinity DataIC50: 750nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [H1047R](Homo sapiens (Human))
Petra Pharma
US Patent
Petra Pharma
US Patent
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Petra Pharma
US Patent
Petra Pharma
US Patent
Affinity DataIC50: 750nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6×his tagged p110<...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [H1047R](Homo sapiens (Human))
Petra Pharma
US Patent
Petra Pharma
US Patent
Affinity DataIC50: <500nMAssay Description:Recombinant, catalytically active human full length PIK3KA Wild-type and H1047R mutant were purchased as 1:1 complex of N-terminal 6× his tagged p110...More data for this Ligand-Target Pair