BDBM605606 US11673893, Example 76-1

SMILES Cc1cnc(NC(=O)[C@H]2CCC[C@H](C2)NC(=O)CC#N)cc1-c1cc(F)c2nn(C)c(c2c1)[C@@](C)(O)C(F)(F)F

InChI Key InChIKey=KBJYBBVTVRWYJU-IRRNSTBUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 605606   

TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM605606(US11673893, Example 76-1)
Affinity DataIC50:  0.780nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK4/Cyc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Prelude Therapeutics

US Patent
LigandPNGBDBM605606(US11673893, Example 76-1)
Affinity DataIC50:  109nMAssay Description:The inhibitory activity of compounds was evaluated in vitro using TR-FRET assay with white 384-well low volume microplate (Greiner Bio-One). CDK2/Cyc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent