BDBM605773 US11673901, Compound 43
SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(C)c(-c3ccc4CCCOc4c3Cl)c3nccn23)[C@@H]1N
InChI Key InChIKey=WLCFBTLKQZYKNH-KSFYIVLOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 605773
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Revolution Medicines
US Patent
Revolution Medicines
US Patent
Affinity DataIC50: <50nMAssay Description:The inhibition of SHP2 by compounds of the invention (concentrations varying from 0.00005-10 μM) was monitored using an assay in which 0.2 nM of...More data for this Ligand-Target Pair