BDBM606114 4-[(1S)-1- aminopropyl]- 2-{6-[(5$#958;)-5- ethyl-6,7- dihydro-5H- pyrrolo[2,1- c][1,2,4]triazol- 3-yl]pyridin-2- yl}-6-[(2R)-2- methylpyrroli- din-1-yl]-2,3- dihydro-1H- pyrrolo[3,4- c]pyridin-1-one::US11684616, Example 16::US11684616, Example 18

SMILES CC[C@H](N)c1nc(cc2C(=O)N(Cc12)c1cccc(n1)-c1nnc2CC[C@@H](CC)n12)N1CCC[C@H]1C

InChI Key InChIKey=CPTADSLPPZGMGJ-HLIPFELVSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 606114   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM606114(4-[(1S)-1- aminopropyl]- 2-{6-[(5$#958;)-5- ethyl-...)
Affinity DataKi: <0.0500nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM606114(4-[(1S)-1- aminopropyl]- 2-{6-[(5$#958;)-5- ethyl-...)
Affinity DataKi:  0.0930nMAssay Description:PRKD2 (PKD2) and RPS6KA2 (RSK3) kinase assays were performed with Km-levels of ATP at the Thermo Fisher Scientific, Inc. (Madison, Wis.), using their...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent