BDBM606835 US11685732, Compound A-20

SMILES Cc1cccc(c1)-c1cc(Cl)c(F)c(c1)C(=O)NNS(=O)(=O)C1CCC(N)C1

InChI Key InChIKey=CWQJUWUEDQFOMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 606835   

TargetHistone acetyltransferase KAT5(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM606835(US11685732, Compound A-20)
Affinity DataIC50: >1.00E+5nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT7(Homo sapiens)
Epizyme

US Patent
LigandPNGBDBM606835(US11685732, Compound A-20)
Affinity DataIC50:  3.00E+4nMAssay Description:Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC50values...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone acetyltransferase KAT6A [507-778](Homo sapiens)
Epizyme

US Patent
LigandPNGBDBM606835(US11685732, Compound A-20)
Affinity DataIC50: >1.00E+5nMAssay Description:KAT-6A. Enzyme assay buffer was 50 mM Tris pH 8.0, 0.002% Tween20, 0.005% bovine skin gelatin, and 1 mM dithiothreitol (DTT). For determination of IC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent