BDBM607544 US11690850, Example 59

SMILES Cc1cc(=O)c(nn1-c1ccccc1F)C(=O)NC1CCc2ccccc2NC1=O

InChI Key InChIKey=OGDQBOYCHJMTGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 607544   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM607544(US11690850, Example 59)
Affinity DataIC50:  33.5nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent