BDBM608517 2-[(3R)-3-amino-3H-spiro[1- benzofuran-2,4'-piperidin]-1'-yl]-5-(2,3- dichlorophenyl)-6-methylpyrimidine-4- carboxamide::US11696916, Compound 122
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1CCC2(CC1)Oc1ccccc1[C@H]2N
InChI Key InChIKey=BLCIDIAYQMYEOC-OAQYLSRUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 608517
Affinity DataIC50: 17nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair