BDBM610414 1-{(R)-2-Hydroxymethyl-4-[2-trifluoromethyl-4-(6-trifluoromethyl-pyridin-3-yl)-thiazol-5-yl]-piperazin-1-yl}-2-(3-isopropyl-[1,2,4]triazol-1-yl)-ethanone::US10053457, Example 10
SMILES CC(C)c1ncn(CC(=O)N2CCN(C[C@@H]2CO)c2sc(nc2-c2ccc(nc2)C(F)(F)F)C(F)(F)F)n1
InChI Key InChIKey=QTGXTHMTKKQHMR-CQSZACIVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 610414
Affinity DataIC50: 961nMAssay Description:Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair