BDBM610418 2-(5-Fluoro-indol-1-yl)-1-{(R)-2-hydroxymethyl-4-[2-trifluoromethyl-4-(2-trifluoromethyl-pyrimidin-5-yl)-thiazol-5-yl]-piperazin-1-yl}-ethanone::US10053457, Example 14
SMILES OC[C@H]1CN(CCN1C(=O)Cn1ccc2cc(F)ccc12)c1sc(nc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F
InChI Key InChIKey=LQRHNGOTLMNBKG-MRXNPFEDSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 610418
Affinity DataIC50: 199nMAssay Description:Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair