BDBM611764 N-(3-chloro-2- fluorophenyl)-1-(3- cyanobenzyl)-1H-1,2,4- triazole-3-carboxamide::US11718612, Example 29

SMILES Fc1c(Cl)cccc1NC(=O)c1ncn(Cc2cccc(c2)C#N)n1

InChI Key InChIKey=SHBLYOMTZBEZSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611764   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM611764(N-(3-chloro-2- fluorophenyl)-1-(3- cyanobenzyl)-1H...)
Affinity DataIC50:  34.1nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent