BDBM611798 US11718612, Example 87

SMILES Cc1ccc(Cn2cnc(n2)C(=O)Nc2cccc(Cl)c2F)cc1F

InChI Key InChIKey=BIHXVWWBZZYXIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611798   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM611798(US11718612, Example 87)
Affinity DataIC50:  32.2nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent