BDBM611803 3-Bromo-6-(3- chloro-2-fluoro- phenyl)-2-(2,5- difluorobenzyl)- 2,4,5,6-tetrahydro- 7H-pyrazolo[3,4-c]- pyridin-7-one::US11718612, Example 101
SMILES Fc1ccc(F)c(Cn2nc3c(CCN(C3=O)c3cccc(Cl)c3F)c2Br)c1
InChI Key InChIKey=GBPWKSNCOCGYMT-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 611803
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 17.4nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair