BDBM611803 3-Bromo-6-(3- chloro-2-fluoro- phenyl)-2-(2,5- difluorobenzyl)- 2,4,5,6-tetrahydro- 7H-pyrazolo[3,4-c]- pyridin-7-one::US11718612, Example 101

SMILES Fc1ccc(F)c(Cn2nc3c(CCN(C3=O)c3cccc(Cl)c3F)c2Br)c1

InChI Key InChIKey=GBPWKSNCOCGYMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611803   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM611803(3-Bromo-6-(3- chloro-2-fluoro- phenyl)-2-(2,5- dif...)
Affinity DataIC50:  17.4nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent