BDBM612311 BDBM612393::BDBM612394::N'-(1,2,3,5,6,7-hexahydro-s-indacen- 4-ylcarbamoyl)-4-(2-hydroxypropan- 2-yl)-5-methylthiophene-2- sulfonimidamide::US11724992, Example 12

SMILES Cc1sc(cc1C(C)(C)O)S(N)(=O)=NC(=O)Nc1c2CCCc2cc2CCCc12

InChI Key InChIKey=HEKHOQRUFCLPIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612311   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612311(BDBM612393 | BDBM612394 | N'-(1,2,3,5,6,7-hexahydr...)
Affinity DataIC50:  120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612311(BDBM612393 | BDBM612394 | N'-(1,2,3,5,6,7-hexahydr...)
Affinity DataIC50:  600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612311(BDBM612393 | BDBM612394 | N'-(1,2,3,5,6,7-hexahydr...)
Affinity DataIC50:  24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent