BDBM612316 BDBM612403::BDBM612404::N'-(4-(difluoromethoxy)-2,6- diisopropylphenylcarbamoyl)-3- fluoro-5-(2-hydroxypropan-2- yl)thiophene-2-sulfonimidamide::US11724992, Example 17

SMILES CC(C)c1cc(OC(F)F)cc(C(C)C)c1NC(=O)N=S(N)(=O)c1sc(cc1F)C(C)(C)O

InChI Key InChIKey=RLCGXXDQRLOCFG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612316   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612316(BDBM612403 | BDBM612404 | N'-(4-(difluoromethoxy)-...)
Affinity DataIC50:  24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612316(BDBM612403 | BDBM612404 | N'-(4-(difluoromethoxy)-...)
Affinity DataIC50:  600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612316(BDBM612403 | BDBM612404 | N'-(4-(difluoromethoxy)-...)
Affinity DataIC50: <8nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent