BDBM612325 BDBM612422::BDBM612423::N'-(8-cyano-1,2,3,5,6,7-hexahydro-s- indacen-4-ylcarbamoyl)-4-(2- hydroxypropan-2-yl)thiophene-2- sulfonimidamide::US11724992, Example 26

SMILES CC(C)(O)c1csc(c1)S(N)(=O)=NC(=O)Nc1c2CCCc2c(C#N)c2CCCc12

InChI Key InChIKey=DLEUBZLVYWJBLI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612325   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612325(BDBM612422 | BDBM612423 | N'-(8-cyano-1,2,3,5,6,7-...)
Affinity DataIC50:  120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612325(BDBM612422 | BDBM612423 | N'-(8-cyano-1,2,3,5,6,7-...)
Affinity DataIC50:  3.00E+3nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612325(BDBM612422 | BDBM612423 | N'-(8-cyano-1,2,3,5,6,7-...)
Affinity DataIC50:  24nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent