BDBM612344 BDBM612460::BDBM612461::N'-(8-fluoro-1,2,3,5,6,7- hexahydro-s-indacen-4- ylcarbamoyl)-4-(2- hydroxypropan-2-yl)-5- methylfuran-2-sulfonimidamide::US11724992, Example 45

SMILES Cc1oc(cc1C(C)(C)O)S(N)(=O)=NC(=O)Nc1c2CCCc2c(F)c2CCCc12

InChI Key InChIKey=XOUZIXOKQCZTTK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612344   

TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612344(BDBM612460 | BDBM612461 | N'-(8-fluoro-1,2,3,5,6,7...)
Affinity DataIC50: <8nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612344(BDBM612460 | BDBM612461 | N'-(8-fluoro-1,2,3,5,6,7...)
Affinity DataIC50:  600nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM612344(BDBM612460 | BDBM612461 | N'-(8-fluoro-1,2,3,5,6,7...)
Affinity DataIC50: <8nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent