BDBM613795 5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-N-(2-methoxyphenyl)furan-2-carboxamide::US11739078, Compound 50::US11739078, Compound B-50

SMILES COc1ccccc1NC(=O)c1ccc(o1)-c1c(ncn1C1CCCC1)-c1ccc(F)cc1

InChI Key InChIKey=BPSYQQWLXMMBAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 613795   

TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613795(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50: <10nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613795(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50:  4.46nMAssay Description:The MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 uM, 10 mM MgAcetate and [gamma-33P-ATP] (specific activity and concentration as r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Insilico Medicine Ip

US Patent
LigandPNGBDBM613795(5-(1-cyclopentyl-4-(4-fluorophenyl)-1H-imidazol-5-...)
Affinity DataIC50:  3.86nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent