BDBM61401 3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydrochloride::3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;hydrochloride::3,3-diphenylpropyl(1-phenylethyl)amine;hydrochloride::CHEMBL254832::FENDILINE HYDROCHLORIDE::MLS000069570::SMR000058827::cid_5702162

SMILES CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=NMKSAYKQLCHXDK-UHFFFAOYSA-N

Data  1 KI  4 IC50  2 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 61401   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataKi:  3.22E+3nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Cavia porcellus)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataKd:  500nMAssay Description:Binding affinity to dansylated bovine testes CaM by fluorescence analysis in presence of calcium2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase(Homo sapiens)
University Of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of ASM (unknown origin)-mediated KRAS mislocalization from plasma membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscriptional activator protein LuxR(Vibrio fischeri)
Insa

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of LuxR-dependent quorum sensing in Vibrio fischeri assessed as reduction of 3-oxo-C6-HSL-induced bioluminescence intensityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 55(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataIC50:  3.10E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCalmodulin(Bos taurus)
Universit£

Curated by ChEMBL
LigandPNGBDBM61401(3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydro...)
Affinity DataEC50:  2.10E+3nMAssay Description:Binding affinity to dansylated bovine brain CaM assessed as half maximal increase in fluorescence by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed