BDBM614150 US11744839, Compound Phloxine B

SMILES [O-]c1c(Br)cc2c(Oc3c(Br)c([O-])c(Br)cc3C22OC(=O)c3c2c(Cl)c(Cl)c(Cl)c3Cl)c1Br

InChI Key InChIKey=ZYIBVBKZZZDFOY-UHFFFAOYSA-L

Data  1 Kd  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614150   

TargetFlavin reductase (NADPH)(Homo sapiens)
Korea Basic Science Institute

US Patent
LigandPNGBDBM614150(US11744839, Compound Phloxine B)
Affinity DataKd:  1.36E+3nMAssay Description:An enzyme activity assay for BLVRB was conducted. Since BLVRB catalyzes the NAD(P)H dependent readuction of FMN, changes in the NAD(P)H concentration...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 614150   

CellFlavin reductase (NADPH)(Homo sapiens)
Korea Basic Science Institute

US Patent
SyringePNGBDBM614150(US11744839, Compound Phloxine B)
ITC DataΔG°: -8.00kcal/mole −TΔS°: -4.11kcal/mole ΔH°: -3.87kcal/mole logk: 7.40E+5
T: 25.00°C 
Syringe InfoPC cidPC sid
In DepthDetails US Patent