BDBM614895 A7-54 rac-2-((3R,4R)-4-(((6- (cyclopropyl(4-(1,1,1,3,3,3- hexafluoro-2-hydroxypropan-2- yl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)acetamide::US20230271937, Example A7-54::US20230271937, Example A7-54-1

SMILES NC(=O)CN1CC[C@@H](CNc2ncnc(N(Cc3ccc(cc3)C(O)(C(F)(F)F)C(F)(F)F)C3CC3)c2F)[C@H](O)C1

InChI Key InChIKey=JYWIABYTODZNJT-MAUKXSAKSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614895   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Nuevolution

US Patent
LigandPNGBDBM614895(A7-54 rac-2-((3R,4R)-4-(((6- (cyclopropyl(4-(1,1,1...)
Affinity DataEC50:  3.80nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Nuevolution

US Patent
LigandPNGBDBM614895(A7-54 rac-2-((3R,4R)-4-(((6- (cyclopropyl(4-(1,1,1...)
Affinity DataEC50:  0.600nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent