BDBM614978 US20230271939, Example 16

SMILES Nc1ncc(cn1)C#Cc1ccnc(NS(=O)(=O)c2cc(Cl)cc(CO)c2Cl)c1F

InChI Key InChIKey=CLVRTGFOLCQHMN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614978   

TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614978(US20230271939, Example 16)
Affinity DataKi:  1.70nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ip2Ipo Innovations

US Patent
LigandPNGBDBM614978(US20230271939, Example 16)
Affinity DataIC50:  111nMAssay Description:The inhibitory activity of the Example compounds towards GCN2 enzyme was measured according to the description below, using a LanthaScreen TR-FRET (T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent