BDBM61867 2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chromen-4-one::5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)-1-benzopyran-4-one::5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromen-4-one::5,6,7,8-tetrahydroxy-2-(4-hydroxyphenyl)chromone::MLS000736839::SMR000528344::cid_96506

SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)c(O)c(O)c(O)c2o1

InChI Key InChIKey=SPZXXUUDYMHBSG-UHFFFAOYSA-N

Data  2 KI  10 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 61867   

LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataKi:  1.29E+3nMAssay Description:Binding affinity to PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataKi:  1.29E+3nMAssay Description:Competitive inhibition of PFKFB3 (unknown origin) using fructose 6-phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlkaline phosphatase, germ cell type(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataEC50:  5.96E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataEC50:  4.34E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIntestinal-type alkaline phosphatase 1(Rattus norvegicus (Rat))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataEC50:  7.19E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50: >1.50E+5nMAssay Description:The inhibitory against activated CDK2-cyclin A2 complex was determined by using the ADP Quest fluorescence assay from (DiscoveRX, Fremont, CA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetT cell receptor alpha variable 4(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50: >9.42E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAlbumin(Bos taurus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50: >9.42E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  5.37E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  341nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  2.97E+3nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2(Homo sapiens (Human))
University Of East Anglia

Curated by ChEMBL
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as phosphate release using Ins(1,3,4,5)P4 as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  2.97E+3nMAssay Description:Inhibition of PFKFB3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataEC50:  8.10E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  1.88E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-like protein 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM61867(2-(4-hydroxyphenyl)-5,6,7,8-tetrakis(oxidanyl)chro...)
Affinity DataIC50:  1.09E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay