BDBM620318 3-(((2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3-methoxy-4-(4-(2,3,4- trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-2-yl)methyl)-1-oxa- 2-azaspiro[4.5]dec-2-ene-8-carbonitrile::US20230295182, Example 1.50

SMILES CO[C@H]1[C@@H](CC2=NOC3(C2)CCC(CC3)C#N)O[C@H](CO)[C@H](O)[C@@H]1n1cc(nn1)-c1ccc(F)c(F)c1F

InChI Key InChIKey=DKURKEAKPKUBBB-JEALBOLUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 620318   

TargetGalectin-1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620318(3-(((2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3...)
Affinity DataIC50:  570nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGalectin-3(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM620318(3-(((2R,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3...)
Affinity DataIC50:  160nMAssay Description:Briefly, compounds are serially diluted in DMSO (working dilutions). ASF-coated 384 well plates are supplemented with 22.8 uL/well of biotinylated hG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent