BDBM621170 US20230303564, Compound 1
SMILES C[C@@]1(O)CCC[C@H]1Nc1nccc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc12
InChI Key InChIKey=UPLMSKBPWUAWBT-DNVCBOLYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 621170
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: 2.72nMAssay Description:Enzymes, substrates, ATP, and inhibitors were diluted by kinase buffer in the kit. The compounds to be tested were diluted 5-fold with a multi-channe...More data for this Ligand-Target Pair
Affinity DataIC50: 0.560nMAssay Description:Enzymes, substrates, ATP, and inhibitors were diluted by kinase buffer in the kit. The compounds to be tested were diluted 5-fold with a multi-channe...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: 2.28nMAssay Description:Preparation of Kinase Buffer: The composition of the buffer: 50 mM of hydroxyethylpiperazine ethanesulfonic acid solution at pH 7.5, 1 mM of ethylene...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: 3.90nMAssay Description:Preparation of Kinase Buffer: The composition of the buffer: 50 mM of hydroxyethylpiperazine ethanesulfonic acid solution at pH 7.5, 1 mM of ethylene...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: 1.67nMAssay Description:Enzymes, substrates, ATP, and inhibitors were diluted by kinase buffer in the kit. The compounds to be tested were diluted 5-fold with a multi-channe...More data for this Ligand-Target Pair