BDBM622557 2′-(((1-(4-fluorobenzyl)-1H-pyrazol-4-yl)methyl)amino)-4′,5′,8′-trimethyl-5′,8′-dihydro-6′H-spiro[cyclopropane-1,7′-pteridin]-6′-one::US20230312587, Compound 223

SMILES CN1C(=O)C2(CC2)N(C)c2nc(NCc3cnn(Cc4ccc(F)cc4)c3)nc(C)c12

InChI Key InChIKey=FQFDEOGSJKJJJA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 622557   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM622557(2′-(((1-(4-fluorobenzyl)-1H-pyrazol-4-yl)met...)
Affinity DataKi: >4.00E+3nMAssay Description:Compounds were screened for their ability to inhibit Plk1 using a radioactive-phosphate incorporation assay. Assays were carried out in a mixture of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent